Education and working experience:
2007.08-2011.06: Zhejiang University,Bachelor
2011.09-2019.03: Zhejiang University,PhD
2019.08-2023.05: Auburn University, U.S.,Visting Scholar, Biosystems Engineering
2023.08-: Assistant Researcher, South Chinese Botanical Garden, Chinese Academy of Sciences
Research field:
Discovery new biosynthetic pathways and key genes for natural plant isopentenyl phenols; study enzyme catalytic mechanisms and engineering better mutants with higher catalytic activities and selectivity. Achieving microbial biosynthesis of isopentenyl phenols via means of synthetic biology and metabolic engineering.
Publications:
[1] Haijiao Wang, Wenqian Liu, Feng Shi, Lei Huang, Jiazhang Lian*, Liang Qu, Jin Cai, Zhinan Xu*, Metabolic pathway engineering for high-level production of 5-hydroxytryptophan in Escherichia coli, Metabolic Engineering, 2018, 48: p.279–287.
[2] Da Xu, Mengjun Fang, Haijiao Wang*, Lei Huang, Qinyang Xu, Zhinan Xu*, Enhanced production of 5-hydroxytryptophan through the regulation of L-tryptophan biosynthetic pathway, Applied Microbiology and Biotechnology. 2020, 104(6):2481-2488.
[3] Wei Liu, Dandan Tang, Haijiao Wang, Jiazhang Lian*, Lei Huang, Zhinan Xu*, Combined genome editing and transcriptional repression for metabolic pathway engineering in Corynebacterium glutamicum using a catalytically active Cas12a, Applied Microbiology and Biotechnology. 2019, 103(21-22):8911-8922.
[4] Feng Xiao, Haijiao Wang, Zhuwei Shi, Qianyue Huang, Lei Huang, Jiazhang Lian*, Jin Cai, Zhinan Xu*, Multi-level Metabolic Engineering of Pseudomonas mutabilis ATCC31014 for Efficient Production of Biotin, Metabolic Engineering, 2020, 61:406-415.
[5] Jun Feng, Jie Zhang, Yuechao Ma, Yiming Feng, Shangjun Wang, Na Guo, Haijiao Wang, Pixiang Wang, Pablo Jiménez-Bonilla, Yanyan Gu, Junping Zhou, Zhong-Tian Zhang, Mingfeng Cao, Di Jiang, Shuning Wang, Xian-Wei Liu, Zengyi Shao, Ilya Borovok, Haibo Huang* & Yi Wang*, Renewable fatty acid ester production in Clostridium, Nature Communications, 2021, 12, 4368.