研究员
您当前的位置：
侯兴亮
研究员/PI/博导
职务：
中心主任/团队负责人
电话：
020-83986636
地址：
广东省广州市天河区兴科路723号
学历/学位：
博士
电子邮件：
houxl@scib.ac.cn
邮政编码：
510650
学习工作简历:
学习经历
2000年至2004年，浙江大学生命科学学院，博士学位；
1997年至2000年，东北农业大学园艺系，硕士学位；
1993年至1997年，东北农业大学园艺系，学士学位。
工作经历
2011年12月-至今，中国科学院华南植物园，研究员，研究组长；
2009年至2011年，新加坡国立大学生物系，博士后；
2006年至2008年，新加坡国立大学与淡马锡生命科学研究所，博士后
研究领域：
研究领域为植物发育分子生物学。
种子是植物生命的起始，决定了植物种族的延续。农业上，种子直接关系到作物的产量和品质，其发育过程是由复杂精确的分子调控网络所决定的。利用分子生物学、生物化学及遗传学方法，我们目前系统研究：1.植物种子发育的分子机理。探索种子发育过程中胚胎与胚乳、合子与母体组织、种子与植株之间的信号交流和互作关系，同时从分子水平上揭示植物激素（赤霉素）参与植物种子等发育与抗性反应过程的内在机制；2.作物品质调控机制研究。探索大豆及甘薯主要品质性状形成的分子基础，克隆关键基因，解析分子调控网络，为改善作物相关经济性状提供理论依据和育种材料。
承担科研项目情况：
1.国家重点研发计划课题“大豆光周期与产量品质形成分子调控机理”，直接经费：300万元，2021.12-2025.12，参加-侯兴亮
2.中科院先导A“种子精准设计的分子基础”项目。直接经费:217万，2019.11-2024.10。主持人: 侯兴亮
3.国家自然科学基金-面上项目“大豆籽粒大小调控基因SW1的克隆及功能研究” （31871643）。直接经费:60万，2019.01-2022.12。主持人:侯兴亮
4.国家自然科学基金-广东联合基金“华南地区甘薯小象甲抗性种质资源 的挖掘与抗虫分子机制研究”（U1701234)。直接经费:275万，2018.01-2021.12。主持人:侯兴亮
5.中科院择优支持经费“植物赤霉素调控的分子机制”。经费：200万2013.01-2015.12。主持：侯兴亮
6.国家自然科学基金“拟南芥NF-YCs基因参与GA介导种子萌发的调控机制”（31370342）。经费：78万，2013.09-2017.12。主持：侯兴亮
7.国家自然科学基金“赤霉素调控胚胎发育的分子机制研究”（31670319）。经费：62万，2016.01-2020.12。主持：侯兴亮
2.中科院先导A“种子精准设计的分子基础”项目。直接经费:217万，2019.11-2024.10。主持人: 侯兴亮
3.国家自然科学基金-面上项目“大豆籽粒大小调控基因SW1的克隆及功能研究” （31871643）。直接经费:60万，2019.01-2022.12。主持人:侯兴亮
4.国家自然科学基金-广东联合基金“华南地区甘薯小象甲抗性种质资源 的挖掘与抗虫分子机制研究”（U1701234)。直接经费:275万，2018.01-2021.12。主持人:侯兴亮
5.中科院择优支持经费“植物赤霉素调控的分子机制”。经费：200万2013.01-2015.12。主持：侯兴亮
6.国家自然科学基金“拟南芥NF-YCs基因参与GA介导种子萌发的调控机制”（31370342）。经费：78万，2013.09-2017.12。主持：侯兴亮
7.国家自然科学基金“赤霉素调控胚胎发育的分子机制研究”（31670319）。经费：62万，2016.01-2020.12。主持：侯兴亮
获奖及荣誉：
2019年，国务院政府特殊津贴
2019年，国家科技创新领军人才
2018年，科技部创新人才推进计划“中青年科技创新领军人才”
2017年，中国科学院优秀研究生指导教师奖
2017年，中国科学院终期评估优秀
2017年，广东特支计划“百千万工程”领军人才
代表论著：
(#共同第一作者，*通讯作者)
1. Xiaoming Li#, Zhonghui Chen#, Haiyang Li#, Lin Yue#, Cuirong Tan, Hongjie Liu, Yilong Hu, Yuhua Yang, Xiani Yao, Lingping Kong, Xiang Huang, Bin Yu, Chunyu Zhang, Yuefeng Guan, Baohui Liu, Fanjiang Kong*, and Xingliang Hou* (2024) Dt1 inhibits SWEET-mediated sucrose transport to regulate photoperiod-dependent seed weight in soybean. Molecular Plant 17, 496-508
2. Guoguo Mei#, Ao Chen#, Yaru Wang, Shuquan Li, Minyi Wu, Yilong Hu, Xu Liu*, and Xingliang Hou* (2024) A simple and efficient in planta transformation method based on the active regeneration capacity of plants. Plant Communications 5, 100822
3. Shu Liu, Zhaojun Liu, Xingliang Hou, and Xiaoming Li* (2023) Genetic mapping and functional genomics of soybean seed protein. Molecular Breeding 43, 29
4. Chunyu Zhang#, Mingyang Jian#, Weijun Li, Xiani Yao, Cuirong Tan, Qian Qian, Yilong Hu, Xu Liu, and Xingliang Hou* (2023) Gibberellin signaling modulates flowering via the DELLA-BRAHMA-NF-YC module in Arabidopsis. The Plant Cell 35, 3470-3484
5. Bin Yu#, Xuemei He#, Yang Tang#, Zhonghui Chen, Limeng Zhou, Xiaoming Li, Chunyu Zhang, Yuhua Yang, Wenbin Zhang, Fanjiang Kong, Xingliang Hou*, and Yilong Hu* (2023) Photoperiod controls plant seed size in a CONSTANS-dependent manner. Nature Plants 9, 343–354
6. Xu Liu#, Yaru Wang#, Hongbo Zhu#, Guoguo Mei#, Yinyin Liao#, Shunfa Rao, Shuquan Li, Ao Chen, Hongjie Liu, Lanting Zeng, Yangyang Xiao, Xiaoming Li, Ziyin Yang, and Xingliang Hou* (2022) Natural allelic variation confers high resistance to sweet potato weevils in sweet potato. Nature Plants 8, 1233-1244
7. Xiali Guo, Jian-Guo Huang*, Valentina Buttò, Dawei Luo, Chunyu Shen, Jingye Li, Hanxue Liang, Shaokang Zhang, Xingliang Hou, Ping Zhao, and Sergio Rossi (2022) Auxin concentration and xylem production of Pinus massoniana in a subtropical forest in south China. Tree Physiology 42, 317-324
8. Yuhua Yang#, Xu Liu#, Wenbin Zhang, Qian Qian, Limeng Zhou, Shu Liu, Yuge Li, and Xingliang Hou* (2021) Stress response proteins NRP1 and NRP2 are pro-survival factors that inhibit cell death during ER stress. Plant Physiology 187, 1414–1427
9. Xiaoming Li#, Chao Fang#, Yongqing Yang#, Tianxiao Lv#, Tong Su#, Liyu Chen, Haiyang Nan, Shichen Li, Xiaohui Zhao, Sijia Lu, Lidong Dong, Qun Cheng, Yang Tang, Meilan Xu, Jun Abe, Xingliang Hou, James L Weller, Fanjiang Kong*, Baohui Liu* (2021) Overcoming the genetic compensation response of soybean florigens to improve adaption and yield at low latitudes. Current Biology 31, 3755-3767
10. Chunyu Zhang, Qian Qian, Xiang Huang, Wenbin Zhang, Xu Liu, and Xingliang Hou* (2021) NF-YCs modulate histone variant H2A.Z deposition to regulate photomorphogenic growth in Arabidopsis. Journal of Integrative Plant Biology 63, 1120-1132
11. Wenbin Zhang, Yang Tang, Yilong Hu, Yuhua Yang, Jiajia Cai, Hailun Liu, Chunyu Zhang, Xu Liu, and Xingliang Hou* (2021) Arabidopsis NF-YCs play dual roles in repressing brassinosteroid biosynthesis and signaling during light-regulated hypocotyl elongation. The Plant Cell 33, 2360-2374
12. Lin Yue#, Xiaoming Li#, Chao Fang#, Liyu Chen#, Hui Yang#, Jie Yang, Zhonghui Chen, Haiyang Nan , Linnan Chen , Yuhang Zhang , Haiyang Li, Xingliang Hou, Zhicheng Dong, James L. Weller, Jun Abe, Baohui Liu, and Fanjiang Kong* (2021) FT5a interferes with the Dt1‐AP1 feedback loop to control flowering time and shoot determinacy in soybean. Journal of Integrative Plant Biology 63, 1004-1020
13. Qian Qian, Yuhua Yang, Wenbin Zhang, Yilong Hu, Yuge Li, Hao Yu, and Xingliang Hou* (2021) A novel Arabidopsis gene RGAT1 is required for GA-mediated tapetum and pollen development. New Phytologist 231, 137-151
14. Yilong Hu#, Limeng Zhou#, Yuhua Yang, Wenbin Zhang, Zhonghui Chen, Xiaoming Li, Qian Qian, Fanjiang Kong, Yuge Li, Xu Liu, and Xingliang Hou* (2021) The gibberellin signaling negative regulator RGA-LIKE3 promotes seed storage protein accumulation. Plant Physiology 185, 1697-1707
15. Hailun Liu#, Yuge Li#, Yilong Hu, Yuhua Yang, Wenbin Zhang, Ming He, Xiaoming Li, Chunyu Zhang, Fanjiang Kong, Xu Liu, and Xingliang Hou* (2021) EDS1-interacting J protein 1 is an essential negative regulator of plant innate immunity in Arabidopsis. The Plant Cell 33, 153-171
16. Yinyin Liao, Lanting Zeng, Shunfa Rao, Dachuan Gu, Xu Liu, Yaru Wang, Hongbo Zhu, Xingliang Hou*, and Ziyin Yang* (2020) Induced biosynthesis of chlorogenic acid in sweetpotato leaves confers the resistance against sweetpotato weevil attack. Journal of Advanced Research 24, 513-522
17. Ying Zhou#, Lanting Zeng#, Xingliang Hou, Yinyin Liao, and Ziyin Yang* (2020) Low temperature synergistically promotes wounding-induced indole accumulation by INDUCER OF CBF EXPRESSION-mediated alterations of jasmonic acid signaling in Camellia sinensis. Journal of Experimental Botany 71, 2172-2185
18. Yuge Li, Yuhua Yang, Yilong Hu, Hailun Liu, Ming He, Ziyin Yang, Fanjiang Kong, Xu Liu, and Xingliang Hou* (2019) DELLA and EDS1 form a feedback regulatory module to fine-tune plant growth-defense tradeoff in Arabidopsis. Molecular Plant 12, 1485-1498
19. He Sun, Zhu Qiao, Khi Pin Chua, Alma Tursic, Xu Liu, Yong-Gui Gao, Yuguang Mu, Xingliang Hou, and Yansong Miao* (2018) Profilin negatively regulates formin-mediated actin assembly to modulate PAMP-triggered plant immunity. Current Biology 28, 1882-1895
20. Yilong Hu, Limeng Zhou, Mingkun Huang, Xuemei He, Yuhua Yang, Xu Liu, Yuge Li, and Xingliang Hou* (2018) Gibberellins play an essential role in late embryogenesis of Arabidopsis. Nature Plants 4, 289-298
21. Xu Liu#, Yuhua Yang#, Yilong Hu, Limeng Zhou, Yuge Li, and Xingliang Hou* (2018) Temporal-specific interaction of NF-YC and CURLY LEAF during the floral transition regulates flowering. Plant Physiology 177, 105-114
22. Xu Liu and Xingliang Hou* (2018) Antagonistic regulation of ABA and GA in metabolism and signaling pathways. Frontiers in Plant Science 9, 251
23. Sijia Lu#, Xiaohui Zhao#, Yilong Hu#, Shulin Liu#, Haiyang Nan#, Xiaoming Li, Chao Fang, Dong Cao, Xinyi Shi, Lingping Kong, Tong Su, Fengge Zhang, Shichen Li, Zheng Wang, Xiaohui Yuan, Elroy R Cober, James L Weller, Baohui Liu*, Xingliang Hou*, Zhixi Tian*, and Fanjiang Kong* (2017) Natural variation at the soybean J locus improves adaptation to the tropics and enhances yield. Nature Genetics 49,773-779
24. Yang Tang#, Xuncheng Liu#, Xu Liu, Yuge Li, Keqiang Wu, and Xingliang Hou* (2017) Arabidopsis NF-YCs mediate the light-controlled hypocotyl elongation via modulating histone acetylation. Molecular Plant 10, 260-273
25. Xu Liu, Pengwei Hu, Mingkun Huang, Yang Tang, Yuge Li, Ling Li, and Xingliang Hou* (2016) The NF-YC–RGL2 module integrates GA and ABA signaling to regulate seed germination in Arabidopsis. Nature Communications 7, 12768
26. Lisha Shen#, Zhe Liang#, Xiaofeng Gu, Ying Chen, Zhi Wei Norman Teo, Xingliang Hou, Weiling Maggie Cai, Peter C. Dedon, Lu Liu, and Hao Yu* (2016) N6-Methyladenosine RNA Modification Regulates Shoot Stem Cell Fate in Arabidopsis. Developmental Cell 38, 186-200
27. Mingkun Huang, Yilong Hu, Xu Liu, Yuge Li, and Xingliang Hou* (2015) Arabidopsis LEAFY COTYLEDON1 mediates postembryonic development via interacting with PHYTOCHROME-INTERACTING FACTOR 4. The Plant Cell 27, 3099-3111
28. Mingkun Huang, Yilong Hu, Xu Liu, Yuge Li, and Xingliang Hou* (2015) Arabidopsis LEAFY COTYLEDON1 controls cell fate determination during post-embryonic development. Frontiers in Plant Science 6, 955
29. Xingliang Hou*, Jiannan Zhou, Chang Liu, Lu Liu, Lisha Shen, and Hao Yu* (2014) Nuclear factor Y-mediated H3K27me3 demethylation of the SOC1 locus orchestrates flowering responses of Arabidopsis. Nature Communications 5, 4601
30. Xingliang Hou*, Lihua Ding, and Hao Yu* (2013) Crosstalk between GA and JA signaling mediates plant growth and defense. Plant Cell Reports 32, 1067-1074
31. Lu Liu#, Chang Liu#, Xingliang Hou, Wanyan Xi, Lisha Shen, Zhen Tao, Yue Wang and Hao Yu* (2012) FTIP1 is an essential regulator required for florigen transport. PLoS Biology 10, e1001313
32. Li Yen Candy Lee#, Xingliang Hou#, Lei Fang, Shuguo Fan, Prakash P. Kumar, and Hao Yu* (2012) STUNTED mediates the control of cell proliferation by GA in Arabidopsis. Development 139, 1568-1576
33. Lei Fang, Xingliang Hou, Li Yen Candy Lee, Lu Liu, Xiaojing Yan, and Hao Yu* (2011) AtPV42a and AtPV42b redundantly regulate reproductive development in Arabidopsis thaliana. PLoS ONE 6, e19033
34. Xingliang Hou, Li Yen Candy Lee, Kuaifei Xia, Yuanyuan Yan, and Hao Yu* (2010) DELLAs modulate jasmonate signaling via competitive binding to JAZs. Developmental Cell 19, 884-894
35. Wanyan Xi#, Chang Liu#, Xingliang Hou, and Hao Yu* (2010) MOTHER OF FT AND TFL1 regulates seed germination through a negative feedback Loop modulating ABA signaling in Arabidopsis. The Plant Cell 22, 1733-1748
36. Xingliang Hou#, Wen-wei Hu#, Lisha Shen, Li Yen Candy Lee, Zhen Tao, Jinhua Han, and Hao Yu* (2008) Global identification of DELLA target genes during Arabidopsis flower development. Plant Physiology 147, 1126-1142
37. Xingliang Hou, Ping Wu*, Fangchan Jiao, Qiaojun Jia, Hanmin Chen, Jie Yu, Xinwei Song, and Keke Yi (2005) Regulation of the expression of OsIPS1 and OsIPS2 in rice via systemic and local Pi signaling and hormones. Plant Cell and Environment 28, 353–364
38. Yu Chao, Hou Xingliang, and Wu Ping* (2005) The effects of phosphorus, glucose and cytokinin on SEN1 gene expression in Arabidopsis. Acta Phytophysiologica Sinica 31, 85-89
39. Ping Wu, Ligeng Ma, Xingliang Hou, Mingyi Wang, Yunrong Wu, Feiyang Liu, and Xingwang Deng* (2003) Phosphate starvation triggers distinct alterations of genome expression in Arabidopsis roots and leaves. Plant Physiology 132, 1260-1271
参编书目：
1. Yuge Li and Xingliang Hou (2017) The Crosstalk of GA and JA: A Fine‐Tuning of the Balance of Plant Growth, Development, and Defense. Mechanism of Plant Hormone Signaling under Stress, Wiley-Blackwell, pp 127-142.