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                Details of the Faculty or staff


Chen Chen





Director of the Regulation of Plant Adaptivity Lab

Job Title


Highest Education



South China Botanical Garden, the Chinese Academy of Sciences Xingke Road #723, Tianhe District, Guangzhou 510650, China



Zip code


Academic Education & Work Career

2020.04 to Now, South China Botanical Garden, Chinese Academy of Science. The Regulation of Plant Adaptivity (Principle Investigator)

2017.04 to 2020.03, London Research and Developmental Centre, Agriculture and Agri-Food Canada. Postdoc

2012.01 to 2017.03, The University of Western Ontario, Canada. Doctor of Philosophy in Biology

2008.09 to 2011.12, Sun Yat-Sen University, China. Graduate Study

2002.09 to 2006.07, Yangzte University, China. Bachelor of Bioengineering

Research Interest

My group is mainly focused on the regulation of transcription machinery in response to different environmental signals in plants. We integrate multiple strategies such as molecular biology, genetics, epigenetics, high-throughput sequencing, and bioinformatics to reveal the molecular mechanisms of transition from transcription initiation to elongation and the real-time responses of transcription machinery to biotic and abiotic stresses. Take advantage of those fundamental discoveries, we expect to provide potential options for improving the adaptivity and sustainability of crops in adverse environmental conditions.

Supported Projects


  1. Chen, C., Shu, J., Li, C., Thapa, R.K., Nguyen, V., Yu, K., Yuan, Z.C., Kohalmi, S.E., Liu, J., Marsolais, F., et al. (2019). RNA polymerase II-independent recruitment of SPT6L at transcription start sites in Arabidopsis. Nucleic Acids Research 47, 6714-6725.
  2. Shu, J.*, Chen, C.*, Thapa, R.K., Bian, S., Nguyen, V., Yu, K., Yuan, Z.C., Liu, J., Kohalmi, S.E., Li, C., et al. (2019). Genome-wide occupancy of histone H3K27 methyltransferases CURLY LEAF and SWINGER in Arabidopsis seedlings. Plant Direct 3, e00100.
  3. Li, C.*, Chen, C.*, Chen, H., Wang, S., Chen, X., and Cui, Y. (2018). Verification of DNA motifs in Arabidopsis using CRISPR/Cas9-mediated mutagenesis. Plant Biotechnol J 16, 1446-1451.
  4. Chen, C.*, Li, C.*, Wang, Y., Renaud, J., Tian, G., Kambhampati, S., Saatian, B., Nguyen, V., Hannoufa, A., Marsolais, F., et al. (2017). Cytosolic acetyl-CoA promotes histone acetylation predominantly at H3K27 in Arabidopsis. Nature Plants 3, 814-824.
  5.  Li, C., Gu, L., Gao, L., Chen, C., Wei, C.Q., Qiu, Q., Chien, C.W., Wang, S., Jiang, L., Ai, L.F., et al. (2016). Concerted genomic targeting of H3K27 demethylase REF6 and chromatin-remodeling ATPase BRM in Arabidopsis. Nature Genetics 48, 687-693.
  6. Li, C., Chen, C., Gao, L., Yang, S., Nguyen, V., Shi, X., Siminovitch, K., Kohalmi, S.E., Huang, S., Wu, K., et al. (2015). The Arabidopsis SWI2/SNF2 chromatin Remodeler BRAHMA regulates polycomb function during vegetative development and directly activates the flowering repressor gene SVP. PLoS Genetics 11, e1004944.

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